产品货号：
Z21302
中文名称：
NANOG抗体
英文名称：
Anti-NANOG Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NANOG Antibody |
| 指标别名 | hNanog;Homeobox protein NANOG;NANOG;Nanog homeobox |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NANOG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NANOG antibody was raised against a 19 amino acid synthetic peptide near the center of human NANOG.The immunogen is located within amino acids 130 - 180 of NANOG. |
| 计算分子量 | 35kDa |
| 成分 | NANOG Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NANOG Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Expression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3.The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases.Artificial stem cells,termed induced pluripotent stem (iPS) cells,can be created by expressing POU5F1 (also known as Oct-4),another germline-specific transcription factor,and the transcription factors Sox2,Klf4 and Lin28 along with c-Myc in mouse fibroblasts.More recently,experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG,Sox2,KlfF4 and c-Myc,eliminating the need for virus introduction,thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. |
| Uniprot ID | Q9H9S0 |
| 基因名全称 | Nanog homeobox |
| 蛋白名全称 | Nanog homeobox |
| 推荐稀释比 | NANOG antibody can be used for detection of NANOG by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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